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Association of Regular and Weekend Warrior Physical Activity Patterns with Gynecologic Cancer Risk: A Cross-Sectional
Jiahui Ye1,2,3, Bixia Zhang2, Qi Yang2
1Guangxi University of Chinese Medicine, Nanning, Guangxi Zhuang Autonomous Region, People's Republic of China.
Regular physical activity (PA) is linked to lower gynecologic cancer risk. The "weekend warrior" PA pattern showed no significant association, warranting further investigation in larger studies.
Area of Science:
- Oncology
- Epidemiology
- Public Health
Background:
- Gynecologic cancers, including cervical, ovarian, and uterine cancers, pose a significant health burden.
- The influence of various physical activity (PA) patterns, such as the
Purpose of the Study:
- To investigate the association between regular and "weekend warrior" physical activity (PA) patterns and the risk of cervical, ovarian, and uterine cancers.
- To explore potential nonlinear relationships and interactions with race/ethnicity.
Main Methods:
- Cross-sectional analysis of 13,675 women from NHANES 2007-2018.
- Weighted multivariable logistic regression and restricted cubic spline (RCS) regression.
- Subgroup analyses stratified by PA patterns and cancer subtypes.
Main Results:
- Regular PA was significantly associated with lower gynecologic cancer prevalence (OR = 0.635).
- The "weekend warrior" PA pattern showed a non-significant association (OR = 0.544).
- Significant nonlinear associations and interactions with race/ethnicity were observed.
Conclusions:
- Regular physical activity may reduce gynecologic cancer risk.
- The impact of the "weekend warrior" PA pattern requires further study due to limited statistical power.
- Consistent PA is crucial for cancer prevention strategies.
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