Reducing Excessive Interdialytic Weight Gain in Young Hemodialysis Patients: A Quality Improvement Initiative

Malek Al Barbandi1, Marissa J DeFreitas1,2, Chryso P Katsoufis1,2

  • 1Holtz Children's Hospital at Jackson Memorial Hospital, Miami, FL.

Kidney Medicine
|November 10, 2025
PubMed

Insights

Excessive interdialytic weight gain (IDWG) in pediatric hemodialysis patients was reduced by 51% using a quality improvement approach. Key interventions included patient education and reduced dialysate sodium, improving outcomes without increasing burden.

Area of Science:

  • Nephrology
  • Pediatric Dialysis
  • Quality Improvement Science

Background:

  • Excessive interdialytic weight gain (IDWG) is a significant risk factor for cardiovascular complications in hemodialysis patients.
  • Current strategies to manage IDWG in pediatric populations require optimization to improve patient outcomes.

Purpose of the Study:

  • To decrease the incidence of excessive IDWG events by 50% over two years in pediatric and young adult hemodialysis patients.
  • To implement and evaluate a multi-interventional quality improvement program targeting IDWG.

Main Methods:

  • A prospective, single-center quality improvement initiative utilizing Plan-Do-Study-Act cycles.
  • Interventions included individualized patient education, nurse-driven communication, monthly IDWG tracking, and a reduction in dialysate sodium concentration.
  • Statistical process control charts and t-tests were used to analyze trends and compare pre- and postintervention data.

Main Results:

  • Excessive IDWG events decreased from 39% at baseline to 19% postintervention, a 51% reduction.
  • Reduced dialysate sodium and enhanced nurse-patient communication demonstrated the most significant impact.
  • No adverse effects were observed on blood pressure, serum sodium levels, or the need for additional dialysis sessions, with minimal increase in nurse documentation time.

Conclusions:

  • A multidisciplinary, multimodal quality improvement intervention effectively reduced excessive IDWG in pediatric hemodialysis patients.
  • Lowering dialysate sodium and implementing nurse-led counseling are effective strategies that do not increase patient treatment burden.
  • Future research should explore the sustainability of these interventions, integration of behavioral health, and long-term cardiovascular outcomes.
Abstract

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