Construction of a Risk Score Model for Predicting Airway Management in Maxillofacial and Neck Region Space Infections
Xijun Wang1,2,3,4,5, Huan Shi1,2,3,4,5, Wentao Qian1,2,3,4,5
1Department of Oral Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, People's Republic of China.
Journal of Inflammation Research
|November 10, 2025
Summary
A new risk scoring system accurately predicts airway management needs in oral and maxillofacial space infections (OMSI). This tool helps identify high-risk patients early, improving outcomes and preventing severe complications like hypoxia.
Area of Science:
- Oral and Maxillofacial Surgery
- Critical Care Medicine
- Medical Informatics
Background:
- Oral and maxillofacial space infections (OMSI) can rapidly progress, leading to life-threatening hypoxia and cardiac arrest.
- Effective airway management is critical for OMSI patients, but predictive tools are lacking.
- Early identification of patients requiring airway intervention is essential to prevent severe complications.
Purpose of the Study:
- To develop and validate a risk scoring system for predicting the need for airway management in patients with OMSI.
- To provide clinicians with a tool for early risk stratification of OMSI patients.
- To improve patient outcomes by enabling timely and appropriate airway interventions.
Main Methods:
- Retrospective study of 215 OMSI patients (January 2020 - December 2022).
- Development of a risk prediction model using LASSO and logistic regression in a training cohort.
- Validation of the model's discrimination and calibration in a separate validation cohort.
Main Results:
- Six independent predictors identified: dyspnea, BMI, body temperature, sIL-2R level, CRP level, and retropharyngeal space involvement.
- The risk scoring system demonstrated good discrimination (AUC 0.91 in training, 0.86 in validation) and calibration.
- Decision curve analysis confirmed the clinical utility of the scoring system.
Conclusions:
- The developed risk scoring system reliably predicts the necessity of airway management in OMSI patients.
- Early identification of high-risk individuals allows for proactive management and improved patient outcomes.
- This validated tool can aid clinicians in optimizing care for patients with OMSI.
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