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Clinical Presentation and Treatment of a Patient With Prurigo Pigmentosa

Dana Rzek¹, Imge Hulur¹

¹Dermatology, Hudson Dermatology, Kingston, USA.

|November 10, 2025

Abstract:

Prurigo pigmentosa is a rare inflammatory condition whose exact etiology is unknown; however, it is often misdiagnosed as eczema, contact dermatitis, or confluent and reticulated papillomatosis. A healthy 18-year-old male presented to the clinic with prurigo pigmentosa that developed after starting a ketogenic diet and intermittent fasting. The diagnosis was based on clinical and histopathologic findings. Treatment with oral minocycline and discontinuation of the diet led to complete resolution with no subsequent recurrence.

Insights

Prurigo pigmentosa is a rare inflammatory skin condition. A case study shows a link between this condition and ketogenic diets, with symptoms resolving after diet cessation and treatment.

Area of Science:

Dermatology
Internal Medicine
Nutritional Science

Background:

Prurigo pigmentosa is a rare inflammatory skin condition.
Its etiology is largely unknown and often misdiagnosed.
Differential diagnoses include eczema, contact dermatitis, and confluent and reticulated papillomatosis.

Read full analysis

Keywords:

keto rash ketogenesis ketogenic diet ketosis nagashima disease prurigo pigmentosa

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