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A Case of Immunotherapy-Induced Balanitis
Terrence Sun1, Danielle Brazel1, Aditya Sarvaria1
1Hematology and Medical Oncology, Scripps Clinic, San Diego, USA.
Cureus
|November 10, 2025
Summary
Pembrolizumab immunotherapy can cause balanitis, a rare but serious skin reaction. This case report demonstrates successful treatment with topical agents, allowing continued cancer therapy and management of side effects.
Area of Science:
- Oncology
- Dermatology
- Immunology
Background:
- Immunotherapy, particularly immune checkpoint inhibitors like pembrolizumab, is a cornerstone in cancer treatment.
- While effective, these therapies can induce a range of immune-related adverse events, including dermatologic toxicities.
- Serious skin reactions, though less common than dermatitis, necessitate careful monitoring and management.
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