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Analyzing Verrucopapillary Lesions of the Oral Cavity: Retracing the Clinicopathological Conundrum
Neetu Jain1, Shashi Keshwar1, Ashish Shrestha1
1Department of Oral Pathology, College of Dental Surgery, B. P. Koirala Institute of Health Sciences, Dharan, Nepal.
Introduction:
In oral cavity, verrucous papillary lesions (VPLs) can be challenging to diagnose both clinically and histopathologically as they share common overlapping features. The most reported VPLs are verrucous carcinoma (VC), verrucous hyperplasia (VH), and squamous papilloma (SP). Inaccurate diagnosis may lead to suboptimal patient outcomes.
Objective:
To evaluate and compare clinicopathological features of reported VPLs to support accurate diagnosis and patient management.
Materials And Methods:
10-year retrospective archival with the histopathologic diagnoses of VPLs was taken. A detailed examination of clinical and histopathological data was compared.
Results:
VC, followed by VH and SP, were the most reported cases. The koilocytic appearance in all cases points towards the viral association of SP. On the other hand, VH and VC seemed to be habit related. It was easy to diagnose SP and verruciform xanthoma (VX). However, VH and VC presented some overlapping features. Also, variations from ideal characteristics were evident in cases of VC.
Conclusion:
The study emphasizes the importance of an accurate biopsy and the accurate diagnosis of benign to malignant VPLs lesions for better treatment and prognosis for the patient.
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