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Reducing the Risk of Targeted Multidrug-Resistant Organism Transmission
1Veterans Health Administration, Kansas City, MO, USA.
Background:
Preventing multidrug-resistant organism (MDRO) transmission in inpatient settings remains challenging due to gaps in infection control practices which facilitate their transmission and compromise patient safety.
Purpose:
This project evaluated the impact of implementing two Centers for Disease Control and Prevention (CDC) guidelines-Management of Multidrug-Resistant Organisms in Healthcare Settings and Isolation Precautions: Preventing Transmission of Infectious Agents in Healthcare Setting-on time to initiation of transmission-based precautions (TBPs) for inpatients who were, or had a history of being, colonized or infected with one or more targeted MDROs.
Methods:
Using a quantitative methodology and quasi-experimental design, pre- and post-implementation data were analyzed via independent samples t-test to assess TBPs initiation times.
Results:
Implementation of the CDC guidelines significantly reduced TBPs initiation times by a mean of 16.32 hours (t (23.21) = 2.91, p = .008). This change reflects both statistical and clinical significance in reducing transmission risk.
Conclusions:
The intervention had a positive impact on time to TBPs initiation. Translation of the CDC guidelines into nursing practice may facilitate timelier identification of patients with MDROs and reduce time to initiation of TBPs, thereby reducing the risk of transmission in the hospital setting.
Insights
Implementing Centers for Disease Control and Prevention (CDC) guidelines significantly reduced the time to initiate transmission-based precautions (TBPs) for patients with multidrug-resistant organisms (MDROs), enhancing patient safety.
Area of Science:
- Healthcare-associated infections
- Infection control
- Epidemiology
Background:
- Preventing multidrug-resistant organism (MDRO) transmission in hospitals is difficult due to infection control practice gaps.
- These gaps increase transmission risk and compromise patient safety.
Purpose of the Study:
- To evaluate the impact of implementing two CDC guidelines on timely initiation of transmission-based precautions (TBPs).
- Focus on inpatients with existing or historical multidrug-resistant organism (MDRO) colonization or infection.
Main Methods:
- Quantitative methodology with a quasi-experimental design.
- Pre- and post-implementation data analyzed using independent samples t-test.
- Assessed time to initiation of transmission-based precautions (TBPs).
Main Results:
- Implementation of CDC guidelines significantly reduced TBPs initiation time by a mean of 16.32 hours.
- The reduction was statistically significant (t(23.21) = 2.91, p = .008).
- This indicates both statistical and clinical significance in reducing transmission risk.
Conclusions:
- The intervention positively impacted time to TBPs initiation.
- Translating CDC guidelines into nursing practice can improve MDRO patient identification.
- This leads to reduced transmission risk in healthcare settings.
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