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Biomarker-guided IL-5 blockade achieves steroid-free MPO-ANCA seroconversion in EGPA
Osamu Matsuno1, Tansri Wibowo1, Yutaka Ishida1
1Department of Allergic and Rheumatoid Disease, Osaka Habikino Medical Center, 3-7-1 Habikino, Osaka, Japan.
Abstract:
This report describes a case of biopsy-confirmed EGPA in which early initiation of mepolizumab, guided by biomarker surveillance, resulted in steroid-free MPO-ANCA seroconversion. These findings suggest a potential steroid-sparing strategy for ANCA-positive EGPA.
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