Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Traumatic Memory

Traumatic Memory

Emotionally traumatic events often lead to memories that are exceptionally vivid and enduring, sometimes persisting with remarkable clarity throughout an individual's life. A classic example of this phenomenon is a person who survives a car accident. Even years later, they may recall every detail of the event with startling accuracy — the screeching of the tires, the jarring impact, and the acrid smell of burning rubber. Such vividness contrasts sharply with how an individual...

Post-traumatic Stress Disorder

Post-traumatic Stress Disorder

Post-traumatic stress disorder (PTSD) is a psychiatric condition that arises following exposure to traumatic events such as natural disasters, forced displacement, or severe accidents. It significantly impairs individuals' ability to cope with daily activities and disrupts their emotional and psychological equilibrium.
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

BDNF-DT and BDNF-AS-DT: novel genes in the BDNF locus.

Molecular psychiatry·2026

Same author

Spatiomolecular mapping reveals anatomical organization of heterogeneous cell types in the human nucleus accumbens.

Neuron·2026

Same author

Glioma-intrinsic MAPK/ERK signaling promotes immunotherapy efficacy through T cell infiltration and interferon responses.

Nature communications·2026

Same author

Co-expression-based models improve eQTL predictions for transcriptome-wide association studies and highlight new schizophrenia-associated genes.

Nature genetics·2026

Same author

Convergent molecular signatures across eating disorders and obsessive-compulsive disorder in the human brain.

Cell reports·2026

Same author

Spatio-molecular gene expression reflects dorsal anterior cingulate cortex structure and function in the human brain.

Cell reports·2026

Search research articles

Related Experiment Video

Updated: Jan 11, 2026

In Vivo Protocol of Controlled Subconcussive Head Impacts for the Validation of Field Study Data

In Vivo Protocol of Controlled Subconcussive Head Impacts for the Validation of Field Study Data

Published on: April 18, 2019

Chronic Traumatic Encephalopathy Neuropathologic Change in Military Veterans.

Grant L Iverson^1,2,3,4,5, Pouya Jamshidi⁶, Amy Deep-Soboslay⁷

¹Department of Physical Medicine and Rehabilitation, Harvard Medical School, Boston, MA 02115, United States.

Military Medicine

|November 10, 2025

Summary

This summary is machine-generated.

Research on chronic traumatic encephalopathy (CTE) in military veterans shows no definitive cases, with only some exhibiting CTE neuropathologic change (CTE-NC) features. Further study is needed to understand CTE prevalence and diagnosis in veterans.

More Related Videos

Author Spotlight: Developing Precise and Clinically Relevant Models for Studying Secondary Degeneration in Traumatic Optic Neuropathy

Author Spotlight: Developing Precise and Clinically Relevant Models for Studying Secondary Degeneration in Traumatic Optic Neuropathy

Published on: November 29, 2024

Development of an Uncomplicated Mild Traumatic Brain Injury Model Modified by Weight-Drop Method and Evidenced by Magnetic Resonance Imaging

Development of an Uncomplicated Mild Traumatic Brain Injury Model Modified by Weight-Drop Method and Evidenced by Magnetic Resonance Imaging

Published on: April 11, 2025

Related Experiment Videos

Last Updated: Jan 11, 2026

In Vivo Protocol of Controlled Subconcussive Head Impacts for the Validation of Field Study Data

In Vivo Protocol of Controlled Subconcussive Head Impacts for the Validation of Field Study Data

Published on: April 18, 2019

Author Spotlight: Developing Precise and Clinically Relevant Models for Studying Secondary Degeneration in Traumatic Optic Neuropathy

Author Spotlight: Developing Precise and Clinically Relevant Models for Studying Secondary Degeneration in Traumatic Optic Neuropathy

Published on: November 29, 2024

Development of an Uncomplicated Mild Traumatic Brain Injury Model Modified by Weight-Drop Method and Evidenced by Magnetic Resonance Imaging

Development of an Uncomplicated Mild Traumatic Brain Injury Model Modified by Weight-Drop Method and Evidenced by Magnetic Resonance Imaging

Published on: April 11, 2025

Area of Science:

Neuroscience
Neuropathology
Military Medicine

Background:

A 2015 meeting identified needs for research on chronic traumatic encephalopathy neuropathologic change (CTE-NC) and clinical diagnostic criteria.
Recent studies have addressed these priorities, yielding significant findings.
This commentary reviews progress and presents new data on CTE-NC in military veterans.

Purpose of the Study:

To review recent research on CTE neuropathologic change (CTE-NC) and clinical diagnostic criteria.
To present new data on CTE-NC in military veterans using brain repository samples.
To assess the prevalence and characteristics of CTE-NC in a cohort of civilian and veteran brain donors.

Main Methods:

Review of recently published studies on CTE.
Analysis of brain tissue samples from the Lieber Institute for Brain Development repository.
Screening of 163 male brain donors (70 military veterans) for definitive CTE-NC or features of CTE-NC.

Main Results:

No cases of definitive CTE-NC were found in the studied cohort.
Features of CTE-NC were identified in 4.3% of civilians and 7.1% of military veterans.
CTE-NC was not associated with depression, suicidality, anxiety, irritability, or other behavioral issues.

Conclusions:

The prevalence of CTE-NC in military veterans remains unclear; it may be uncommon.
Validated clinical diagnostic criteria for CTE are still lacking.
Current evidence does not link CTE-NC to specific psychiatric or behavioral conditions.