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Updated: Jan 11, 2026

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals
Published on: December 16, 2022
Microvascular Dysfunction Assessed by 82 Rb PET/CT as a Diagnostic Tool of Chronic Active Myocarditis
Matthieu Bailly1,2, Aurélie Sannier3,4, Phalla Ou5,6
1Nuclear Medicine Department, CHU ORLEANS.
Abstract:
Immune-related myocarditis may be challenging. We report the case of a 66-year-old man with a history of treated multiple myeloma by using immune checkpoint blockers, referred for angina. Coronary angiography was normal. [ 82 Rb]Rubidium PET/CT found diffuse abnormal stress myocardial blood flow and reserve and the apparition of epicardial calcifications. [ 68 Ga]Ga-DOTATOC PET/CT and CMR revealed chronic calcified myocarditis, which was confirmed by histology. This case emphasizes microvascular dysfunction in chronic active myocarditis as assessed by perfusion PET/CT.
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