The preliminary European multi-centre experience with G-Branch Endograft

Area of Science:

• Vascular Surgery
• Endovascular Repair
• Aortic Aneurysm Treatment

Background:

• Thoraco-abdominal aortic aneurysms (TAAA) and juxta/pararenal abdominal aortic aneurysms (J/PAAA) present complex treatment challenges.
• Novel endovascular devices are crucial for improving outcomes in complex aortic pathologies.

Purpose of the Study:

• To evaluate the short-term safety and efficacy of a novel, customized multibranched G-Branch endograft.
• To assess outcomes for patients undergoing endovascular repair of TAAA and J/PAAA.

Main Methods:

• A multicenter study involving 50 patients treated with the G-Branch endograft between July 2023 and May 2025.
• Patients had either TAAA (31) or J/PAAA (19), with some requiring repair of concomitant iliac or arch aneurysms.
• Procedures included elective one-stage (60%) or staged repair (40%), with data collected prospectively and analyzed retrospectively.

Main Results:

• High technical success rate of 96% (48/50) was achieved.
• Early perioperative complications occurred in 11% of patients, with no spinal cord ischemia.
• Over a mean 7-month follow-up, freedom from branch instability was 99%, with only 4% requiring reintervention for endoleaks.

Conclusions:

• The G-Branch endograft demonstrates safety and high technical success in the preliminary treatment of J/PAAA and TAAA.
• Encouraging short-term outcomes suggest potential for this device in complex aortic aneurysm repair.
• Continued surveillance and extended follow-up are necessary to validate long-term efficacy.