Related Experiment Video
Updated: Jan 6, 2026

Augmenting Large Language Models via Vector Embeddings to Improve Domain-Specific Responsiveness
Published on: December 6, 2024
Artificial Intelligence Chatbots and Their Responses to Most Searched Spanish Cancer Questions
En Cheng1,2, Jesus D Anampa3,4, Carolina Bernabe-Ramirez3,4
1Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, USA.
Background:
Artificial intelligence (AI) chatbots perform well in answering English cancer questions. For Spanish, their performance is unknown and may differ by free vs. paywall versions.
Methods:
We evaluated the quality (range: 1-5 points), actionability (range: 0-100%), and readability (range: 1-13 grades) of six popular AI chatbots in responding to the 15 most searched Spanish questions regarding breast, prostate, and colon cancer.
Results:
The quality of overall AI chatbot responses was good (mean [95% CI]: 3.5 [3.4-3.6] points), while the actionability was low (mean [95% CI]: 35.6% [30.8%-40.3%]). The readability was high-school-level (mean [95% CI]: 9.2 [8.8-9.6] grades), not concordant with the American Medical Association recommendation (≤ 6th grade). The quality, actionability, and readability did not differ by free and paywall versions (p > 0.05).
Conclusion:
Our findings suggested AI chatbots may generate good-quality responses to Spanish cancer questions, regardless of free or paywall versions. However, further improvement in actionability and readability is needed to benefit Spanish-speaking patients.
More Related Videos
05:47Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
07:46Microfluidic Co-Culture Models for Dissecting the Immune Response in in vitro Tumor Microenvironments
Published on: April 30, 2021
Related Concept Videos
Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Cancer Prevention
Some...
What is Cancer?
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of...
Tumor Immunotherapy
Mouse Models of Cancer Study
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
Cancer