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Lyophilization enables thermostable formulation of dengue virus-derived defective interfering particles

Min-Hsuan Lin1, Pramila Maniam2, Bing Tang2

  • 1Program of Infection and Inflammation, QIMR Berghofer Medical Research Institute, Herston, Queensland, 4006, Australia; Global Virus Network (GVN) Center of Excellence, Australian Infectious Disease Research Centre, Brisbane, St Lucia, Queensland, 4067, Australia; Centre for Tropical Health & Emerging Diseases, Herston, Queensland, 4006, Australia.

Antiviral Research
|November 10, 2025
PubMed

Keywords:
Defective interfering particles (DIPs)Defective viral genome (DVG)Dengue virus (DENV)Field-deployable RNA therapyInterferon-stimulated genes (ISGs)Lyophilization

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