Differences in Impulse Oscillometry Parameters Measured Using Different Devices

Area of Science:

• Pulmonary Function Testing
• Respiratory Physiology
• Medical Device Comparison

Background:

• Limited data exist on absolute and percent predicted impulse oscillometry (IOS) values across different devices.
• Understanding device-specific IOS performance is crucial for accurate interpretation in chronic respiratory diseases.

Purpose of the Study:

• To compare impulse oscillometry (IOS) values and percent predicted values between MasterScreen-IOS and MostGraph-02 devices.
• To assess the agreement and correlation of IOS measurements obtained from two different devices in patients with COPD and asthma.

Main Methods:

• Retrospective analysis of IOS data from 54 subjects (asthma and COPD) using both MasterScreen-IOS and MostGraph-02.
• Paired sample t-tests and Pearson's correlation were used for comparing IOS values.
• Bland-Altman analysis determined the limits of agreement between the two devices.

Main Results:

• Significant differences were observed in absolute and percent predicted reactance values, including resonant frequency (Fres) and area under the reactance curve (AX), between the two devices.
• MasterScreen-IOS yielded higher reactance values compared to MostGraph-02.
• Discrepancies were noted in percent predicted values for resistance heterogeneity (R5-R20), Fres, and AX.

Conclusions:

• Significant differences in IOS reactance values exist between MasterScreen-IOS and MostGraph-02 devices.
• Device-specific reference equations likely contribute to variations in percent predicted values.
• IOS measurements from these devices should be interpreted cautiously and are not interchangeable for longitudinal assessments.