Ivermectin treatment for nasal myiasis complicated by orbital cellulitis: a case report

Nasal myiasis is a rare parasitic infestation caused by fly larvae, which can lead to serious complications, such as orbital cellulitis, if not treated promptly. Early recognition and intervention are essential to prevent further complications.

We present a case of a 55-year-old Thai female with advanced-stage malignant melanoma of the right nasal cavity, treated with endoscopic tumor removal and 3 months of concurrent chemoradiation. The patient developed nasal myiasis and orbital cellulitis secondary to maggot infestation. A multidisciplinary approach, including adjunctive therapy with ivermectin, resulted in the successful resolution of both the infestation and its complications.

This case highlights the effectiveness of ivermectin in treating nasal myiasis and emphasizes the importance of a collaborative medical approach in managing complex cases. It also provides insights into the mechanism and clinical application of ivermectin for similar parasitic infestations.