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Updated: Jan 11, 2026
Author Spotlight: Exploring Non-Motor Symptoms in Parkinson's Disease
Published on: September 22, 2023
Non-Motor Symptoms in Parkinson's Disease and Their Impact on Quality of Life: A Cross-Sectional Study
Suhail Ahsan1, Sahil Mehta2, Kamalesh Chakravarti2
1Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Background:
Non-motor symptoms have a more significant impact on the quality of life in Parkinson's disease than motor symptoms.
Objectives:
To evaluate the frequency of non-motor symptoms in Parkinson's disease and study their impact on quality of life.
Methods:
A cross-sectional study was conducted on 100 patients with idiopathic Parkinson's disease. All patients underwent a detailed history and neurological examination, Hoehn and Yahr staging, MDS UPDRS scoring, NMSS scoring, and PDQ-39 scoring to assess their quality of life.
Results:
All patients presented with at least one non-motor symptom. The most frequently affected non-motor symptom was sleep/fatigue (95%), followed by urinary (79%) and gastrointestinal dysfunction (76%). The total NMSS score significantly correlated with disease severity and quality of life.
Conclusion:
Non-motor symptoms are quite prevalent in patients with Parkinson's disease and significantly impact their quality of life.
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