Related Experiment Video
Updated: Jul 21, 2026

The Terroir Concept Interpreted through Grape Berry Metabolomics and Transcriptomics
Published on: October 5, 2016
Metabolomics-based analysis of the regulatory effects of Dendrobium nobile Lindl. on key bioactive metabolites during
Jiana Tan1, Lin Zhang1, Lanyan Cen1
1School of Liquor and Food Engineering, Guizhou University, Guiyang, China.
Background:
Dendrobium nobile Lindl. (DNL), a traditional Chinese medicinal herb with abundant bioactive compound content, possesses significant pharmacological potential. However, its regulatory effects on the metabolic profile of fermented rice wine under different fermentation strategies remain largely unexplored.
Results:
Metabolomic analysis demonstrated that DNL supplementation increased the diversity and abundance of key bioactive metabolites significantly, particularly terpenoids, flavonoids, alkaloids, and phenolic compounds, with the most notable enhancement observed in sequential fermentation. Multivariate statistical analyses confirmed distinct clustering of metabolic profiles, underscoring DNL's role in reshaping the fermentative metabolome. Metabolic pathway analysis revealed that DNL primarily modulated alkaloid and terpenoid biosynthesis by regulation of phenylalanine, tryptophan, and histidine metabolism, as well as the limonene and pinene degradation pathways, with Kyoto Encyclopedia of Genes and Genomes (KEGG) mapping identifying biosynthesis of secondary metabolites (sce01110) and phenylalanine metabolism (sce00360) as central regulatory nodes.
Conclusion:
This study elucidates the mechanism by which DNL enhances the functional properties of rice wine through targeted regulation of critical metabolic pathways. These findings provide a scientific foundation for the development of value-added functional beverages and offer new insights into the application of medicinal herbs in fermented food products. © 2025 Society of Chemical Industry.
More Related Videos
08:03A Tandem Liquid Chromatography–Mass Spectrometry-based Approach for Metabolite Analysis of Staphylococcus aureus
Published on: March 28, 2017
07:36Analysis of Raw and Processed Cyperi Rhizoma Samples Using Liquid Chromatography-Tandem Mass Spectrometry in Rats with Primary Dysmenorrhea
Published on: December 23, 2022
Related Concept Videos
Fates of Pyruvate
In aerobic organisms, pyruvate is metabolized via the citric acid cycle to produce reduced coenzymes NADH and FADH2. These coenzymes are then oxidized in the electron transport chain to produce ATP and, in the process, regenerate the NAD+ and FAD. As seen in some cell types and organisms, fermentation...
Microbial Fermentation
Microbes in Food Production
Microbes in Beverage Production
Bioreactor Controls-III
Production of Alcohol