Isolated Unilateral Ovarian Metastasis from Breast Cancer Demonstrated by ¹⁸F-FDG PET/CT

A 49-year-old premenopausal woman with a history of left modified radical mastectomy and axillary lymph node dissection for invasive lobular carcinoma three years ago, underwent ¹⁸F-fluorodeoxyglucose positron emission tomography/computed tomography (¹⁸F-FDG PET/CT) due to gradually increasing CA15-9 and CEA levels during routine follow-up. Compared with previous ¹⁸F-FDG PET/CT images, the left ovary in the current images showed increased size and radiotracer uptake. Subsequently, total abdominal hysterectomy and bilateral salpingo-oophorectomy were performed, and histopathological evaluation confirmed unilateral metastasis in the left ovary due to primary breast cancer. Although rare, possible isolated ovarian metastasis should be considered in patients with breast cancer who have increased size and radiotracer uptake in ovarian tissue on follow-up ¹⁸F-FDG PET/CT scans.