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Dual-Bionic Wearable Platform with Neighborhood Electrochemical Biosensor and Janus Fabric for Unidirectional Sweat
Chaohuan Yang1, Shuyi Li1, Chenchen Liao1
1Key Laboratory of Bionic Engineering (Ministry of Education), Jilin University, Changchun, 130022, China.
Advanced Healthcare Materials
|November 11, 2025
Summary
This study presents a comfortable wearable biosensor platform for sweat analysis. It effectively monitors glucose and lactate, offering a promising tool for sports and biomedical applications.
Area of Science:
- Biomedical Engineering
- Materials Science
- Electrochemistry
Background:
- Wearable sensors require optimal skin comfort and sensitivity for effective sweat detection.
- Monitoring biomarkers like glucose and lactate in sweat is crucial for sports and health diagnostics.
Purpose of the Study:
- To develop a comfortable wearable platform for real-time sweat analysis.
- To create a highly sensitive electrochemical biosensor for glucose and lactate detection.
Main Methods:
- Fabrication of a biomimetic Janus patterned cotton fabric (PCF) for unidirectional sweat transport.
- Construction of a 3D neighborhood electrochemical biosensor using electrochemical deposition and drop-casting.
- Utilizing nanostructured composite electrodes with molecular docking simulations to confirm interactions.
Main Results:
- The Janus PCF facilitated efficient water transport from skin to the biosensor.
- The biosensor achieved high sensitivities for glucose (3.4 nA·µm-1) and lactate (0.21 µA·mm-1).
- Nanostructured electrodes demonstrated improved electron transfer and stability, successfully anchoring oxidase enzymes.
Conclusions:
- The developed wearable biosensor platform effectively collects and analyzes human sweat.
- This technology offers a promising strategy for future applications in sports science and biomedicine.
