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Directed Evolution of a Nonheme Iron Enzyme to Access Chiral α-Amino Acid Derivatives by 1,3-Migratory Nitrene

Minghui Cheng1, Tao Li1, Yamei Gan1

  • 1School of Biotechnology and Key Laboratory of Industrial Biotechnology of Ministry of Education, Jiangnan University, Wuxi, 214122, China.

Angewandte Chemie (International Ed. in English)
|November 11, 2025
PubMed

Keywords:
1,3‐migrationBiocatalysisDirected evolutionNitrene C─H insertionNonheme iron enzymes

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