Solitary Neurocysticercosis: A Challenging Diagnosis, a Simple Treatment

Neurocysticercosis (NCC), caused by the larval stage of Taenia solium, is the most common parasitic infection of the central nervous system and a major cause of adult-onset epilepsy in endemic regions. While typically presenting with multiple brain lesions, solitary parenchymal lesions can occur and may mimic tumors, abscesses, or granulomatous diseases, especially in non-endemic settings where clinician familiarity is low. We report the case of a young Filipino woman living in Saudi Arabia who presented with new-onset seizures and a solitary parietal lesion. Limited epidemiologic risk factors and atypical imaging findings delayed diagnosis until histopathology confirmed NCC. This case underscores the importance of including NCC in the differential diagnosis of solitary brain lesions even in non-endemic regions.