Neurodevelopment and Risk Factors in Infants Before, During, and After the COVID-19 Pandemic in Eastern China: Cross-Sectional Study
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View abstract on PubMed
Summary
This summary is machine-generated.The COVID-19 pandemic increased infant neurodevelopmental delays, with risks continuing post-pandemic. Early interventions are crucial for mitigating long-term effects on child development.
Area Of Science
- Pediatric Neurodevelopment
- Epidemiology
- Public Health
Background
- Emerging evidence suggests a link between COVID-19 pandemic exposure and heightened risks of neurodevelopmental disorders in infants.
- Population-based studies on these associations in Chinese contexts, especially post-pandemic, are limited.
Purpose Of The Study
- To analyze dynamic changes in infant neurodevelopment in eastern China across different COVID-19 pandemic phases.
- To identify key risk factors contributing to infant neurodevelopmental delays.
Main Methods
- Cross-sectional study of 17,621 Peabody Developmental Motor Scales-II (PDMS-II) and 7877 Bayley Scales of Infant Development-Chinese Cities Revised (BSID-CR) assessments (Jan 2019-Jul 2023).
- Multivariate logistic regression analyzed associations between pandemic phases (prepandemic, pandemic, postpandemic), seasonality, and perinatal variables with neurodevelopmental outcomes.
Main Results
- Infants during the pandemic (stage II) and postpandemic (stage III) showed significantly higher risks of neurodevelopmental delays compared to the prepandemic phase.
- The postpandemic phase exhibited the highest risk for mental development delay.
- Cesarean delivery, male gender, and low birth weight were identified as independent risk factors for neurodevelopmental delay.
Conclusions
- The COVID-19 pandemic significantly exacerbated infant neurodevelopmental vulnerabilities, with effects persisting into the postpandemic era.
- Public health strategies focusing on early interventions are recommended to address these long-term impacts.
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