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07:34
Intravital Microscopy of the Inguinal Lymph Node
Published on: April 4, 2011
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Unicentric Castleman disease in intraparotid lymph node: a case report
Young Heon Jeong1, Jin Seok Kim1, Heonwoo Lee2
1Department of Oral and Maxillofacial Surgery, College of Medicine, University of Ulsan, Seoul, Republic of Korea.
Maxillofacial Plastic and Reconstructive Surgery
|November 11, 2025
Summary
Castleman disease (CD) is a rare lymphoproliferative disorder. Unicentric Castleman disease (UCD) involving the parotid gland, though rare, can mimic tumors, but surgical excision offers a cure.
Area of Science:
- Oncology
- Pathology
- Otolaryngology
Background:
- Castleman disease (CD) is a rare lymphoproliferative disorder.
- Unicentric Castleman disease (UCD) typically presents as a solitary mass.
- Intraparotid lymph node involvement is rare and can mimic salivary gland neoplasms.
Purpose of the Study:
- To highlight the rare presentation of UCD in the parotid gland.
- To discuss diagnostic challenges and management of parotid UCD.
- To emphasize the importance of considering CD in parotid masses.
Main Methods:
- Case presentation of a 35-year-old female with a parotid mass.
- Contrast-enhanced CT for imaging.
- Conservative surgical excision with facial nerve preservation.
- Histopathological evaluation for diagnosis.
Main Results:
- Confirmed hyaline-vascular variant of UCD.
- Postoperative regression of lymphadenopathy.
- Resolution of transient facial nerve palsy.
Conclusions:
- CD should be considered in the differential diagnosis of parotid masses.
- Recognizing clinical and radiologic features aids diagnosis.
- Complete surgical excision is curative for UCD.
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