Related Experiment Video
Updated: Jan 6, 2026
08:16
High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model
Published on: March 16, 2022
3.9K
Active limb-protection in type A aortic dissection complicated by lower-extremity malperfusion
Shohei Yoshida1, Julia Glizevskaja2, Bobby H N Chow2
1Division of Cardiothoracic Surgery, Department of Surgery, University of Washington Medical Center, Seattle, WA, USA.
Perfusion
|November 11, 2025
Summary
Acute type A aortic dissection can cause severe lower extremity ischemia. A multidisciplinary approach prioritizes early extremity reperfusion alongside central aortic repair to prevent complications and improve outcomes.
Area of Science:
- Cardiovascular Surgery
- Vascular Surgery
- Aortic Diseases
Background:
- Lower extremity ischemia in acute type A aortic dissection leads to severe complications like amputation, acute kidney injury, and mortality.
- Timely reperfusion is crucial, balancing risks of delayed extremity blood flow restoration versus postponed central aortic repair.
Purpose of the Study:
- To present a multidisciplinary strategy for managing lower extremity ischemia in acute type A aortic dissection.
- To minimize ischemia-reperfusion injury while ensuring definitive aortic repair.
Main Methods:
- Implementing a multidisciplinary team approach.
- Performing early extremity reperfusion concurrently with central aortic repair.
Main Results:
- Reduced complications associated with lower extremity ischemia.
- Minimized ischemia-reperfusion injury.
- Successful definitive aortic management.
Conclusions:
- A multidisciplinary approach with early extremity reperfusion is effective for acute type A aortic dissection with lower extremity ischemia.
- This strategy balances urgent aortic repair with limb salvage, improving patient outcomes.
Related Concept Videos
01:23Peripheral Artery Disease V: Postoperative Nursing Management
343
During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
343
01:21Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
311
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
311
01:27Peripheral Artery Disease III: Interprofessional Care
215
Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
215
01:30Peripheral Artery Disease I: Introduction
275
Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
275
01:26Aneurysm III: Interprofessional Care
233
Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
233
01:26Peripheral Artery Disease IV: Nursing Management
306
The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses,...
306