Related Experiment Video
Updated: Jan 11, 2026

Retropinacol/Cross-pinacol Coupling Reactions - A Catalytic Access to 1,2-Unsymmetrical Diols
Published on: April 4, 2014
Electroreductive C(sp3)-C(sp3) Cross-Coupling Reactions
Min Liu1, Wentao Zhang1, Pengfei Li1
1State Key Laboratory of Elemento-Organic Chemistry, College of Chemistry, Nankai University, Tianjin 300071, China.
Abstract:
The construction of C(sp3)-C(sp3) bonds represents a fundamental and ongoing challenge in synthetic chemistry. Electrochemistry, which employs electric current as a traceless redox agent, offers a promising alternative to conventional methods─combining environmental benefits and renewable energy utilization with precise control over reaction selectivity. In recent years, these advantages have been successfully leveraged in a growing number of C(sp3)-C(sp3) bond-forming reactions. This perspective summarizes recent advances in the electrochemical reductive approach to such bond formations and offers a perspective on future directions for the field.
More Related Videos
11:44Mizoroki-Heck Cross-coupling Reactions Catalyzed by Dichloro{bis[1,1',1''-phosphinetriyltripiperidine]}palladium Under Mild Reaction Conditions
Published on: March 20, 2014
06:34Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides CHIPS
Published on: June 20, 2014
Related Concept Videos
Thermal Electrocyclic Reactions: Stereochemistry
Selection Rules: Thermal Activation
Conjugated systems containing an even number of π-electron pairs undergo a conrotatory ring closure. For example, thermal electrocyclization of (2E,4E)-2,4-hexadiene, a conjugated diene containing two π-electron pairs, gives trans-3,4-dimethylcyclobutene.
Thermal and Photochemical Electrocyclic Reactions: Overview
Photochemical Electrocyclic Reactions: Stereochemistry
Selection Rules: Photochemical Activation
Cycloaddition Reactions: Overview
Crossed Aldol Reactions: Overview
Benzene to 1,4-Cyclohexadiene: Birch Reduction Mechanism