[Adult pertussis: an emerging clinical problem requiring urgent attention]
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View abstract on PubMed
Summary
This summary is machine-generated.Pertussis (whooping cough) is rising in China, especially endangering infants. Adults often unknowingly spread pertussis to babies, highlighting the need for better adult diagnosis and treatment.
Area Of Science
- Infectious Diseases
- Public Health
- Microbiology
Background
- Global resurgence of pertussis (whooping cough) noted.
- China experiencing increased pertussis cases over the last decade.
- Infants under three months are most vulnerable, with severe cases and fatalities concentrated in this group.
Purpose Of The Study
- To increase clinician awareness of adult pertussis.
- To reduce diagnostic delays and oversights in adult pertussis cases.
- To discuss interrupting transmission from adults to infants.
Main Methods
- Review of current pertussis epidemiology.
- Analysis of underdiagnosis and diagnostic challenges in adult pertussis.
- Examination of rational antibiotic use amid macrolide-resistant *Bordetella pertussis*.
Main Results
- Adults are a primary source of pertussis infection for infants.
- Pertussis in adults is frequently underdiagnosed and overlooked.
- Macrolide resistance in *Bordetella pertussis* complicates treatment decisions.
Conclusions
- Early diagnosis and treatment of pertussis in adults are crucial.
- Interrupting adult-to-infant transmission requires improved adult case recognition.
- Strategies for managing pertussis must consider antibiotic resistance patterns.
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