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[Brain activity alterations in chronic cough: a resting-state functional magnetic resonance imaging study]

Z Chen1, C Zhan1, L Long1

  • 1Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Guangzhou Medical University, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, Guangzhou 510120, China.

Zhonghua Jie He He Hu Xi Za Zhi = Zhonghua Jiehe He Huxi Zazhi = Chinese Journal of Tuberculosis and Respiratory Diseases
|November 11, 2025
PubMed
Summary

Patients with chronic cough show altered brain activity, particularly in cerebellar regions, suggesting central sensitization. These brain changes differ between refractory chronic cough and somatic cough syndrome, indicating distinct hypersensitivity mechanisms.

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