Related Experiment Video
Updated: Jan 11, 2026
A Structured Approach to Extubation in Mechanically Ventilated Rats
Published on: July 18, 2025
On-Table Extubation following Cardiac Surgery: Clinical Outcomes and Associated Cost Reductions from a Single
John Tobia1, Russell Pepe1, Fady Soliman2
1Division of Cardiothoracic Surgery, Department of Surgery, Robert Wood Johnson University Hospital, New Brunswick, NJ.
Objective:
To determine whether extubation timing influences clinical outcomes and resource utilization.
Design:
A retrospective observational cohort study.
Setting:
A single academic medical center in the United States.
Participants:
Patients who underwent cardiac surgery between January 2020 and December 2023 and were extubated with either on-table extubation (OTE) or early extubaion (EE).
Interventions:
None, as this study was a retrospective analysis of clinical practice data comparing two extubation strategies.
Measurements And Main Results:
Of 2014 patients meeting inclusion criteria, 1026 (50.9%) underwent OTE. At baseline, OTE patients had fewer comorbidities and less frequent combined procedures than EE patients. After adjustment for baseline characteristics, OTE was associated with a significantly shorter hospital length of stay (regression coefficient -0.78 days; 95% CI -1.2 to -0.36; p < 0.001) and lower direct hospital costs (regression coefficient -$3,029; 95% CI -$4,831 to -$1,227; p = 0.001). There were no significant differences in reintubation, intensive care unit readmission, discharge mortality, 30-day mortality, or initial intensive care unit hours between groups.
Conclusions:
OTE is a safe and effective alternative to EE in appropriately selected cardiac surgery patients, associated with shorter hospitalization and reduced cost without compromising patient safety. Further prospective studies are warranted to validate these findings and identify predictors of OTE success.
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