Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Dialysis01:27

Dialysis

1.2K
Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
1.2K
Dialysis01:15

Dialysis

1.6K
Dialysis is a diffusion-based purification process that separates analyte molecules from a complex matrix. This is accomplished by allowing molecules in the solution to pass through a semipermeable membrane into a liquid on the other side. The membrane is usually made of cellulose acetate or cellulose nitrate, and the second liquid must be miscible with the solution. Ions (e.g., chloride or sodium) or organic molecules (e.g., glucose) can pass through the membrane pores, which generally have...
1.6K
Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis01:30

Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis

379
Patients with end-stage renal disease (ESRD) or those experiencing drug overdose often require extracorporeal methods to eliminate accumulated drugs and metabolites. Hemoperfusion, hemofiltration, and dialysis are the primary techniques to rapidly remove harmful substances without disrupting the patient's fluid and electrolyte balance. For those with compromised renal function, dosage adjustments of concurrent medications may be necessary during extracorporeal drug removal.Dialysis is a process...
379
Acute Kidney Injury V: Interprofessional Care01:20

Acute Kidney Injury V: Interprofessional Care

287
Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
287
Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy01:26

Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy

166
Continuous Renal Replacement Therapy (CRRT) is an essential intervention for patients experiencing severe kidney dysfunction. This therapy offers a continuous mechanism for removing fluids and toxins from the bloodstream, leveraging the patient’s blood pressure to facilitate filtration through a specialized filter. This method contrasts with intermittent dialysis, providing a gentler and more consistent removal of waste products and excess fluid, which is particularly beneficial in...
166
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications01:25

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

503
Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...
503

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mid-Term Exposure to Air Pollution and Acute Kidney Injury Incidence: A 10-Year Study in Eastern Poland.

Journal of clinical medicine·2026
Same author

Renal Cell Carcinoma of Native Kidneys in Kidney Allograft Recipients: Are There Any Guidelines for Management?

Journal of clinical medicine·2026
Same author

Renal Dose Adjustment in European Primary Care: Clinical Nuances and Practical Challenges.

Journal of clinical medicine·2026
Same author

Cognitive Performance After Kidney and Liver Transplantation: A Cross-Sectional Study Using Addenbrooke's Cognitive Examination III.

Journal of clinical medicine·2026
Same author

Diagnosis of Sporadic Creutzfeldt-Jakob Disease in Both Kidney Recipients From the Same Donor: Was It Graft Transmission?

Cureus·2026
Same author

Rituximab in a desensitization protocol as a rescue therapy in severe nephrotic syndrome-a case report.

Journal of nephrology·2026

Related Experiment Video

Updated: Jan 11, 2026

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice
06:27

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice

Published on: July 20, 2022

3.1K

Sustained low-efficiency dialysis-an old method but possibly a new solution for environmental nephrology.

Aleksandra Rymarz1, Filip Wantoch-Rekowski1, Paweł Żebrowski1

  • 1Department of Nephrology, Dialysis and Internal Medicine, Medical University of Warsaw, Warsaw, Poland.

Renal Failure
|November 11, 2025
PubMed
Summary

Slow low-efficiency dialysis (SLED) offers a sustainable kidney replacement therapy. This hybrid technique provides unique advantages in efficacy and safety for intensive care unit patients.

Keywords:
CRRTSLEDacute kidney injurygreen nephrology

More Related Videos

Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis
07:11

Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis

Published on: July 19, 2018

15.9K
5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
05:34

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

1.5K

Related Experiment Videos

Last Updated: Jan 11, 2026

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice
06:27

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice

Published on: July 20, 2022

3.1K
Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis
07:11

Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis

Published on: July 19, 2018

15.9K
5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
05:34

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

1.5K

Area of Science:

  • Nephrology
  • Critical Care Medicine

Background:

  • Slow low-efficiency dialysis (SLED) is a hybrid kidney replacement therapy.
  • It bridges the gap between intermittent and continuous therapies.

Purpose of the Study:

  • To summarize the technical aspects and practical advantages of SLED.
  • To present clinical experiences with SLED in challenging critical care scenarios.
  • To highlight SLED's unique benefits for intensive care unit (ICU) kidney care.

Main Methods:

  • SLED can be performed using mobile batch dialysis systems or standard hemodialysis machines.
  • Key features include reduced dialysate flow and extended procedure duration.

Main Results:

  • SLED demonstrates efficacy and safety in complex clinical conditions.
  • Successful application noted in intraoperative renal replacement therapy during liver transplantation.
  • Effective in managing sepsis and heart failure patients with volume overload.

Conclusions:

  • SLED offers unique advantages in efficacy, safety, and sustainability for ICU kidney replacement therapy.
  • It represents a valuable and sustainable option for critical care nephrology.