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Related Experiment Video

Updated: Jul 28, 2026

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery

Published on: April 14, 2016

Individualized cognitive behavioral therapy for chronic pain in Japan: study protocol for a multicenter randomized

Hiroki Hosogoshi^1,2, Kazunori Iwasa³, Takaki Fukumori⁴

¹Faculty of Sociology, Kansai University, Suita, Japan. hosogosh@kansai-u.ac.jp.

|November 11, 2025

Summary

This study shows that a brief, face-to-face Cognitive Behavioral Therapy for Chronic Pain (CBT-CP) program improved quality of life in Japanese adults. This evidence supports wider adoption of CBT-CP in Japan.

Keywords:

Chronic pain Cognitive behavioral therapy Japan Mediators and moderators Multicenter randomized controlled trial Psychosocial outcomes Psychotherapy Quality of life Study protocol

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Related Experiment Videos

Last Updated: Jul 28, 2026

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery

Published on: April 14, 2016

Dynamic Quantitative Sensory Testing to Characterize Central Pain Processing

Dynamic Quantitative Sensory Testing to Characterize Central Pain Processing

Published on: February 16, 2017

Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research

Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research

Published on: January 5, 2024

Area of Science:

Pain Management
Psychological Therapies
Clinical Trials

Background:

Chronic pain significantly burdens individuals and society.
Cognitive Behavioral Therapy for Chronic Pain (CBT-CP) is effective internationally, but evidence from Japan is limited.
Previous Japanese trials used different formats (e.g., videoconference, longer duration) with pain intensity as the primary outcome.

Purpose of the Study:

To evaluate the effectiveness of a brief, face-to-face, individualized CBT-CP program in Japan.
To determine if CBT-CP improves quality of life (QoL) in adults with chronic pain.
To provide randomized evidence for CBT-CP implementation in Japan.

Main Methods:

An open-label, randomized, parallel-group superiority trial involving 60 adults with chronic pain.
Participants were randomized to either treatment as usual (TAU) plus an eight-session CBT-CP program or a waitlist control receiving TAU only.
The primary outcome was QoL, measured by the EQ-5D-5L at 15±2 weeks. Secondary outcomes included pain intensity, disability, and depressive symptoms.

Main Results:

The study is designed to clarify the added value of a brief, fidelity-assured, face-to-face CBT-CP program.
Results are expected to guide clinical adoption and workforce training for CBT-CP in Japan.
The trial will also explore potential mediators and moderators of treatment benefit.

Conclusions:

This trial will provide crucial randomized evidence on the efficacy of a brief, face-to-face CBT-CP program in Japan.
Findings are anticipated to inform clinical practice, training, and dissemination strategies for CBT-CP.
The study aims to generate hypotheses regarding patient subgroups and mechanisms through which CBT-CP confers benefits.