Changes in Anxiety and Depression in Patients with an Acute Myocardial Infarction that Received Treatment by

Tomoaki Hama1, Kaho Hashimoto2, Tadahiro Goto3,4

  • 1Division of Cardiology, Department of Medicine, Tokai University Hachioji Hospital, Tokyo, Japan.

JMA Journal
|November 12, 2025
PubMed

Insights

Mental health in acute myocardial infarction (AMI) patients improved with the ABCDEFGH bundle. Anxiety scores decreased, but depression persisted post-discharge, affecting 34% of patients.

Area of Science:

  • Cardiology
  • Psychiatry
  • Health Services Research

Background:

  • Mental health disorders like anxiety and depression are common in acute myocardial infarction (AMI) patients.
  • The effectiveness of specific treatments for these conditions in AMI patients remains unclear.
  • The ABCDEFGH bundle, incorporating continuous nurse-led follow-up, is a comprehensive approach to patient care.

Purpose of the Study:

  • To evaluate changes in anxiety and depression over time in AMI patients treated with the ABCDEFGH bundle.
  • To determine the post-discharge prevalence of anxiety and depression in these patients.
  • To assess the impact of percutaneous coronary intervention (PCI) and the ABCDEFGH bundle on mental health outcomes.

Main Methods:

  • A retrospective cohort study of 29 AMI patients who underwent PCI and received ABCDEFGH bundle treatment.
  • Anxiety and depression were assessed using the Hospital Anxiety and Depression Scale (HADS) in the ICU, general ward, and outpatient department (OPD).
  • Statistical analysis compared HADS scores across different care phases and determined post-discharge prevalence.

Main Results:

  • Anxiety scores (HADS-A) significantly improved from ICU to OPD (6.4 to 3.9, p=0.001).
  • Depression scores (HADS-D) showed no significant changes between ICU, general ward, and OPD (ranging from 5.2 to 6.7).
  • Post-discharge, 14% of patients experienced anxiety and 34% experienced depression.

Conclusions:

  • The ABCDEFGH bundle treatment, including PCI, led to improved anxiety levels in AMI patients.
  • Depression remained a significant issue, with a high prevalence post-discharge, indicating a need for targeted interventions.
  • Continuous follow-up and comprehensive care bundles may help manage anxiety but require further investigation for depression in AMI survivors.
Abstract

Related Concept Videos

Acute Coronary Syndrome IV: Interprofessional Care01:28

Acute Coronary Syndrome IV: Interprofessional Care

IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
205
Angina V: Nursing Management01:20

Angina V: Nursing Management

Angina, a symptom of myocardial ischemia, requires a structured nursing management approach to ensure effective care and prevent complications like myocardial infarction. Comprehensive nursing care involves assessing, diagnosing, planning, implementing interventions, and evaluating outcomes, all tailored to the individual patient's needs.Patient AssessmentNursing assessment begins with a detailed subjective evaluation of symptoms, which typically include chest pain or pressure radiating to the...
281
Acute Coronary Syndrome V: Nursing Management01:26

Acute Coronary Syndrome V: Nursing Management

Nursing Assessment:Nursing management of acute coronary syndrome (ACS) involves taking the patient's history, focusing on primary complaints such as chest pain, dyspnea, and excessive sweating (diaphoresis), as well as other symptoms like back or jaw pain, nausea, vomiting, palpitations, dizziness, and fatigue. The nurse also reviews the patient's history of cardiac events, risk factors such as hypertension, diabetes, smoking, family history, and current medications.In the objective assessment,...
257
Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
207
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
200
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
333