Related Experiment Video
Updated: Jan 11, 2026

Depolymerizable Olefinic Polymers Based on Fused-Ring Cyclooctene Monomers
Published on: December 16, 2022
The high potential of methyl laurate as a recyclable competitor to conventional toxic solvents in [3 + 2]
Ayhan Yıldırım1, Mustafa Göker1
1Department of Chemistry, Bursa Uludağ University, Bursa 16059, Turkey.
Abstract:
In the present study, 21 fused isoxazolidines were synthesized in yields ranging from good to excellent. Methyl laurate was identified as the easily accessible optimal solvent medium for the reaction, and the related compounds were obtained through straightforward isolation techniques in a relatively short time frame (5-80 minutes). A comprehensive investigation was conducted utilizing various web platforms, encompassing ecological and environmental risk assessments, toxicity, pesticide similarity, and biodegradability of methyl laurate in comparison with a series of conventional organic solvents, water, some fatty acids and their derivatives. The findings of this investigation revealed that methyl laurate exhibited better green solvent properties when evaluated against other solvents.
More Related Videos
Related Concept Videos
Cycloaddition Reactions: MO Requirements for Thermal Activation
Cycloaddition Reactions: Overview
Cycloaddition Reactions: MO Requirements for Photochemical Activation
Olefin Metathesis Polymerization: Acyclic Diene Metathesis (ADMET)
Similar to cross-metathesis, ADMET also involves the formation of metallacyclobutane intermediate by [2+2] cycloaddition of one of the double bonds of a terminal diene with...
[4+2] Cycloaddition of Conjugated Dienes: Diels–Alder Reaction
Preparation of Alkynes: Alkylation Reaction
Alkylation of terminal alkynes with primary alkyl halides in the presence of a strong base like sodium amide is one of the common methods for the synthesis of longer carbon-chain alkynes. For example, treatment of 1-propyne with sodium amide followed by reaction with ethyl bromide yields 2-pentyne.

