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Lactobacillus casei's Antitumor Potential in Colorectal Cancer: Exploring Mechanisms-A Systematic Review
Mahdi Abdorrashidi1, Mohammad Heiat2, Amin Vesal Yeganeh1
1Student Research Committee, Baqiyatallah University of Medical Sciences, Tehran, Iran, bmsu.ac.ir.
Lactobacillus casei (L. casei) strains show potential for preventing and treating colorectal cancer (CRC). This review explores L. casei mechanisms, suggesting its use in combination therapy to complement standard CRC treatments.
Area of Science:
- Oncology
- Microbiology
- Gastroenterology
Background:
- Colorectal cancer (CRC) is a leading cause of cancer death globally, with current treatments having limitations.
- Alternative strategies for CRC prevention and treatment are needed, prompting research into probiotics.
- Lactobacillus casei (L. casei) strains are being investigated for their potential anticancer effects in CRC.
Conclusions:
- Specific L. casei strains possess promising anticancer properties against CRC through various biological mechanisms.
- These findings support the development of L. casei-based probiotic supplements as an adjunct therapy for CRC.
- Combining L. casei with conventional treatments may offer a novel and effective approach for CRC management.
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