Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multiscale artificial spider web for comprehensive pressure sensing and human-machine interaction.

Nature communications·2026
Same author

Highly selective and sensitive uric acid sensor based on a self-assembled CdS/CdIn<sub>2</sub>S<sub>4</sub> heterojunction.

Nanoscale·2025
Same author

A Multimodal Sensory Textile Using Programmable Ferroelectric Nanocomposites.

Advanced materials (Deerfield Beach, Fla.)·2025
Same author

Wide-range human physiological signal acquisition with carbonized composite nanofibers.

Nanoscale·2025
Same author

Implantable and Biodegradable Smart Textiles for Continuous Limb and Gastrointestinal Motility Monitoring.

Small (Weinheim an der Bergstrasse, Germany)·2025
Same author

Decorating Biaxially Oriented PVDF Nanocomposites with Ultralow Contents of Functionalized BNNSs for Excellent Energy Storage.

ACS applied materials & interfaces·2025

Related Experiment Video

Updated: Jan 11, 2026

Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor
08:22

Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor

Published on: February 16, 2018

12.5K

A Sweat Cortisol Sensor Based on Gold-Modified Molecularly Imprinted Polymer.

Ziyu Liu1,2, Guangzhong Xie1, Jing Li1

  • 1State Key Laboratory of Electronic Thin Films and Integrated Devices, School of Optoelectronic Science and Engineering, University of Electronic Science and Technology of China, Chengdu 610054, China.

Nanomaterials (Basel, Switzerland)
|November 12, 2025
PubMed
Summary

A new portable electrochemical cortisol sensor (PECS) offers accurate mental stress assessment. This device enables non-invasive, real-time monitoring of mental health, addressing a critical public health need.

Keywords:
cortisol sensorelectrochemistrymolecular imprintingscreen printing electrodesweat

More Related Videos

A Detailed Protocol for Perspiration Monitoring Using a Novel, Small, Wireless Device
05:32

A Detailed Protocol for Perspiration Monitoring Using a Novel, Small, Wireless Device

Published on: November 24, 2016

8.2K
A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay
12:31

A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay

Published on: February 28, 2015

15.6K

Related Experiment Videos

Last Updated: Jan 11, 2026

Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor
08:22

Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor

Published on: February 16, 2018

12.5K
A Detailed Protocol for Perspiration Monitoring Using a Novel, Small, Wireless Device
05:32

A Detailed Protocol for Perspiration Monitoring Using a Novel, Small, Wireless Device

Published on: November 24, 2016

8.2K
A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay
12:31

A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay

Published on: February 28, 2015

15.6K

Area of Science:

  • Biomedical Engineering
  • Analytical Chemistry
  • Neuroscience

Background:

  • Depressive disorders affect 3.8% of the global population, a challenge worsened by the COVID-19 pandemic.
  • Objective quantification of psychological states is difficult, highlighting the need for reliable stress assessment tools.
  • Current methods for mental stress assessment lack objectivity and real-time capabilities.

Purpose of the Study:

  • To develop a portable electrochemical cortisol sensor (PECS) for accurate mental stress assessment.
  • To create a non-invasive and real-time method for monitoring mental health.
  • To address the limitations of existing stress assessment techniques.

Main Methods:

  • Developed a portable electrochemical cortisol sensor (PECS).
  • Utilized a screen-printed carbon electrode modified with gold nanoparticles.
  • Synthesized a molecularly imprinted polymer (MIP) via electropolymerization for cortisol detection.

Main Results:

  • The PECS exhibited a wide linear detection range from 1 fM to 1 μM.
  • Achieved an ultra-low detection limit of 0.4112 fM.
  • Demonstrated high sensitivity of 15.518 nA∙lg(nM-1)∙cm-2.

Conclusions:

  • The developed PECS provides an accurate and sensitive method for mental stress assessment.
  • This technology offers a new possibility for soft bioelectronics in non-invasive, real-time mental health monitoring.
  • PECS can contribute to addressing the public health challenge posed by mental health disorders.