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Evaluation of an Exclusive Spur Dike U-Turn Design with Radar-Collected Data and Simulation
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Sensing danger at the bridge
1Department of Infectious Diseases, Faculty of Life Sciences & Medicine, King's College London, London, UK.
Abstract:
NoCut safeguards genome integrity against persistent DNA bridges, but how these missegregation events are sensed is not understood. In this issue, Dam et al. (https://doi.org/10.1083/jcb.202502014) identify the Srs2 and PARI helicases as conserved NoCut sensors that initiate signalling to delay cytokinetic abscission.
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