Related Experiment Video
Updated: Jan 6, 2026
07:20
Inducement and Evaluation of a Murine Model of Experimental Myopia
Published on: January 22, 2019
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One-Year Efficacy and Tolerance of Myofix Defocus Spectacles for Control of Myopia Progression
Rafael Iribarren1,2,3, Abel Szeps4, Carlos Kotlik5
1Novar, Miami, USA. rafairibarren@gmail.com.
Ophthalmology and Therapy
|November 12, 2025
Summary
Myofix Defocus spectacles effectively slowed myopia progression in children over one year. Good compliance significantly enhanced the treatment effect, showing a notable reduction in refractive error and axial length changes compared to controls.
Area of Science:
- Ophthalmology
- Pediatric Optometry
- Myopia Management
Background:
- Childhood myopia is a growing public health concern.
- Effective myopia control strategies are crucial for preventing high myopia and associated complications.
- Myofix Defocus spectacles represent a novel approach to myopia control.
Purpose of the Study:
- To evaluate the 1-year efficacy of Myofix Defocus spectacles in controlling childhood myopia progression.
- To identify risk factors influencing myopia progression in children using these spectacles.
- To compare the efficacy of Myofix Defocus spectacles against virtual control groups.
Main Methods:
- A cohort of 47 children (aged 7-15 years) with myopia were enrolled.
- Cycloplegic refraction (SE) and axial length (AL) were measured at baseline, 6, and 12 months.
- Linear regression models analyzed risk factors; compliance and tolerance were assessed.
Main Results:
- Myofix Defocus spectacles showed a mean SE change of -0.21 D and AL change of 0.19 mm over 12 months.
- Good compliance was associated with significantly better outcomes (SE: -0.12 D, AL: 0.17 mm).
- Compliant participants demonstrated a 75% reduction in SE and 37% reduction in AL compared to virtual controls.
Conclusions:
- Myofix Defocus spectacles are effective in slowing myopia progression in children over 1 year.
- Treatment efficacy is strongly linked to patient compliance.
- Further long-term studies are recommended to validate these findings.
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