[Treatment and eradication of Helicobacter pylori infection in Primary Care]

To describe the therapy used for Helicobacter pylori (HP) infection and obtain the eradication rate in primary care (PC).

Descriptive cross-sectional observational study conducted at the Florida Primary Care Centre in L'Hospitalet de Llobregat (Barcelona). The study population consisted of patients aged 15 years or older with HP infection, and the variables were: active ingredients prescribed and their regimen, evaluation of eradication 28 days after diagnosis, sex, age, and country of origin.

In 2018-2019-2020, 1,023 cases of HP were diagnosed, 65.4% (669) were women, mean age 47.17 years (SD 15.7; range 15-93), 56.9% of Spanish origin and 28.3% from Latin America. Quadruple therapy without bismuth with omeprazole 20 mg (OCAM20) was prescribed in 27.4% of the total, classic triple therapy with omeprazole 20 mg (OCA20) in 15%, and quadruple therapy with a single three-in-one capsule containing metronidazole, tetracycline, and bismuth (MTB) with omeprazole in 14.3%. In 15.9% of cases, no treatment was recorded, and in 9.3% of cases, an incorrect regimen was found. Verification tests were performed in 614 cases. It was found that OCA20 achieved an eradication rate of 82.3%, OCA with 40 mg/12 hours achieved 89.8%, OCAM20 achieved 88.0% and MTB achieved 84.7%, with no statistically significant differences between regimens (p=0.674).