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Updated: Jul 18, 2026

Genetic Manipulation of Cerebellar Granule Neurons In Vitro and In Vivo to Study Neuronal Morphology and Migration
Published on: March 17, 2014
Myeloid TET2 tips the balance of neuro-epithelial crosstalk
Maria Backhaus1, Kai Markus Schneider1
1Department of Medicine I, Else Kroener Fresenius Center for Digital Health, and Center for Regenerative Therapies Dresden (CRTD), University Medical Center Dresden, TUD Dresden University of Technology, Dresden, Germany; Department of Medicine III, University Hospital RWTH Aachen, Aachen, Germany.
Abstract:
Sympathetic signaling has been implicated in colitis, but the precise circuits remain unclear. In this issue of Immunity, Sharma et al. demonstrate that myeloid cell-specific loss of DNA-demethylation dampens sympathetic signaling-driven colitis exacerbation in an IL-1β-dependent manner.
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