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Enhanced trial efficiency of the novel "contemporaneous control recapture" parallel-cohort RCT design: Methods and

Anthony A Sochet1, Ernest K Amankwah2, Vahid Andalib3

  • 1Division of Pediatric Critical Care Medicine, Johns Hopkins All Children's Hospital, St. Petersburg, FL, United States; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States; Johns Hopkins All Children's Institute for Clinical and Translational Research, St. Petersburg, FL, United States.

Contemporary Clinical Trials
|November 12, 2025
PubMed

Keywords:
Parallel cohortPhase 3Randomized clinical trialRare diseaseTrial efficiency

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