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Comparative Outcomes of Acute Type B Aortic Dissection and Intramural Hematoma: Implications for Surgical and
Byeng Hun Jeon1, Tae Hong Yoon1, Kyung Ho Kim1
1Department of Thoracic and Cardiovascular Surgery, School of Medicine, Daegu Catholic University, Daegu, Republic of Korea.
Insights
Acute type B aortic syndrome (ATBAS), encompassing aortic dissection (AD) and intramural hematoma (IMH), shows distinct natural histories. While thoracic endovascular aortic repair (TEVAR) improves remodeling, it does not enhance survival for either condition.
Area of Science:
- Cardiovascular Medicine
- Vascular Surgery
- Radiology
Background:
- Acute type B aortic syndrome (ATBAS), including type B aortic dissection (AD) and intramural hematoma (IMH), often follows shared management guidelines.
- However, limited comparative data exist regarding their distinct natural histories and outcomes.
Purpose of the Study:
- To compare the clinical characteristics, management, and aortic remodeling patterns of patients with AD and IMH.
- To evaluate the long-term outcomes of medical management versus thoracic endovascular aortic repair (TEVAR) in ATBAS.
Main Methods:
- Retrospective review of 131 patients with ATBAS (52 AD, 79 IMH) treated between 2008 and 2025.
- Stratification into interventional (TEVAR) and medical management groups.
- Serial computed tomography (CT) assessment of aortic growth using standardized protocols and regression analysis.
Main Results:
- IMH patients were older than AD patients (70.6 vs. 60.5 years).
- Medically managed patients with AD showed a higher rate of delayed intervention (13.5%) compared to IMH (6.7%), primarily due to progressive enlargement.
- TEVAR improved aortic remodeling in both AD and IMH but did not significantly impact survival rates. Aortic diameter changes correlated with false lumen or hematoma thickness.
Conclusions:
- AD and IMH exhibit different remodeling patterns despite similar management guidelines.
- Conservative management is effective for selected uncomplicated cases.
- TEVAR offers remodeling benefits without survival improvement in ATBAS, though early intervention may be beneficial for progressive AD.
Background:
Acute type B aortic syndrome (ATBAS), including type B aortic dissection (AD) and intramural hematoma (IMH), shares management guidelines; however, their natural history may differ. Comparative single-center data are limited.
Methods:
We retrospectively reviewed 131 patients with ATBAS (52 with AD and 79 with IMH) treated from 2008 to 2025. Patients were stratified into interventional (thoracic endovascular aortic repair [TEVAR]) and medical groups. Serial computed tomography at 3 thoracic levels was performed using standardized protocols, with aortic growth assessed by smoothing and mixed-effects regression.
Results:
Patients with IMH were older than those with AD (70.6 ± 12.3 vs. 60.5 ± 16.1 years; P = 0.0002), with modest early TEVAR rates (28.8% vs. 24.1%). Among medically managed patients, delayed intervention occurred in 13.5% and 6.7% of patients with AD and IMH. Indications differed: progressive enlargement in AD and heterogeneous causes in IMH. Mean time to intervention was longer in patients with AD (18.5 months; 3.2 months excluding one outlier) than in those with IMH (3.0 months). TEVAR promoted favorable remodeling in both diseases but did not improve survival. IMH prevalence was higher than that in Western cohorts, aligning with Asian data. Changes in the aortic diameter were strongly linked to false lumen thickness in AD and hematoma thickness in IMH.
Conclusion:
Despite similar guidelines, AD and IMH exhibit distinct remodeling patterns. Conservative therapy remains effective in selected uncomplicated cases, whereas TEVAR improves remodeling without a survival benefit. Progressive enlargement in uncomplicated AD suggests that performing TEVAR in early stages is beneficial.
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