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Neural Representation of Episodic Time
Sze Chai Kwok1, Regina C Lapate2, John J Sakon3
1Phylo-Cognition Laboratory, DKU - The First People's Hospital of Kunshan Joint Brain Sciences Laboratory, Digital Innovation Research Center, Division of Natural and Applied Sciences, Duke Kunshan University, Kunshan 215316, China sze-chai.kwok@st-hughs.oxon.org.
Abstract:
Inspired by recent discoveries of neural populations that track time for specific moments (time cells) and elapsed durations (temporal context and periodic time cells), this review, based on a minisymposium presented at the 2025 annual meeting of the Society for Neuroscience, brings together macro-, meso-, and micro-scale neural evidence to formulate hypotheses about how episodic time-the tracking and organizing of events in time as we experience, store, and retrieve them from memory-is coded and processed in the mammalian brain. We also discuss computational principles and relationships to other related phenomena such as memory replay and emotional states.
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