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Multiple, Segmental, Non-Syndromic Basal Cell Carcinomas-Clinical, Dermoscopic and Histopathological Features
Martyna Sławińska1, Beata Zagórska1, Wojciech Biernat2
1Department of Dermatology, Venereology and Allergology, Faculty of Medicine, Medical University of Gdańsk, 80-214 Gdańsk, Poland.
Diagnostics (Basel, Switzerland)
|November 13, 2025
Summary
This case report details a rare instance of segmental/agminated basal cell carcinoma (BCC) presenting as multiple amelanotic tumors. It highlights unique dermoscopic findings for this uncommon skin cancer presentation.
Area of Science:
- Dermatology
- Oncology
- Dermopathology
Background:
- Basal cell carcinoma (BCC) is the most common skin cancer.
- Amelanotic BCC can be challenging to diagnose clinically.
- Segmental/agminated BCC is a rare morphologic variant.
Purpose of the Study:
- To describe the clinical and dermoscopic features of a rare case of segmental/agminated basal cell carcinoma.
- To contribute to the understanding of amelanotic BCC diagnosis.
- To document the 3-year follow-up of this rare condition.
Main Methods:
- Case presentation of a 72-year-old woman with multiple amelanotic lesions.
- Clinical examination and dermoscopy of the lesions.
- Histopathological confirmation of basal cell carcinoma.
- 3-year follow-up for recurrence.
Main Results:
- Four amelanotic tumors on the left arm were diagnosed as basal cell carcinoma via histopathology.
- Dermoscopy revealed polymorphic and arborizing vessels with non-specific malignant features.
- No recurrence was observed during the 3-year follow-up period.
Conclusions:
- Segmental/agminated basal cell carcinoma is a rare diagnosis for multiple clustered pink tumors.
- This is the first report detailing the dermoscopic features of this rare BCC subtype.
- Dermoscopy can aid in the diagnosis of challenging amelanotic BCC presentations.
