Related Experiment Video

Updated: May 6, 2026

Human Primary Trophoblast Cell Culture Model to Study the Protective Effects of Melatonin Against Hypoxia/reoxygenation-induced Disruption
12:02

Human Primary Trophoblast Cell Culture Model to Study the Protective Effects of Melatonin Against Hypoxia/reoxygenation-induced Disruption

Published on: July 30, 2016

16.4K

Special Issue "Recent Molecular Research on Preeclampsia"

Natalia Ivanovna Agalakova1

  • 1Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, 44 Thorez Avenue, 194223 Saint-Petersburg, Russia.

International Journal of Molecular Sciences
|November 13, 2025
PubMed

Insights

Preeclampsia is a serious pregnancy complication causing organ damage. This study investigates its underlying mechanisms and potential therapeutic targets for better maternal health outcomes.

Area of Science:

  • Obstetrics and Gynecology
  • Cardiovascular Research
  • Nephrology

Background:

  • Preeclampsia (PE) is a significant cause of maternal morbidity and mortality worldwide.
  • Characterized by new-onset hypertension and proteinuria after 20 weeks of gestation, PE involves widespread organ and vascular damage.
  • The exact pathophysiology of PE remains incompletely understood, necessitating further research.

More Related Videos

The 4-vessel Sampling Approach to Integrative Studies of Human Placental Physiology In Vivo12:17

The 4-vessel Sampling Approach to Integrative Studies of Human Placental Physiology In Vivo

Published on: August 2, 2017

11.1K
Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles05:31

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles

Published on: January 26, 2024

1.2K

Related Concept Videos

Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
891