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Noninvasive Assessment of Cardiac Abnormalities in Experimental Autoimmune Myocarditis by Magnetic Resonance Microscopy Imaging in the Mouse
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The Contemporary Role of Cardiovascular Magnetic Resonance in Ischemic Cardiomyopathy

Desak Gede Widyawati1, Lynette L S Teo2, Ching Ching Ong2

  • 1National University Heart Centre, National University Hospital, Singapore 119074, Singapore.

Journal of Clinical Medicine
|November 13, 2025
PubMed

Insights

Cardiovascular magnetic resonance (CMR) offers a comprehensive assessment of ischemic cardiomyopathy, aiding in diagnosis and treatment decisions. Emerging AI approaches promise to further enhance its clinical utility in managing heart failure.

Area of Science:

  • Cardiovascular imaging and diagnostics
  • Heart failure research
  • Medical artificial intelligence

Background:

  • Ischemic cardiomyopathy is the primary cause of heart failure worldwide.
  • Echocardiography is standard, but cardiovascular magnetic resonance (CMR) provides superior detail on cardiac structure and function.
  • CMR overcomes imaging limitations and radiation concerns associated with other modalities.

Purpose of the Study:

  • To review the established diagnostic and prognostic value of CMR in ischemic cardiomyopathy.
  • To explore novel quantitative and AI-driven techniques in CMR for ischemic heart disease.
  • To highlight CMR's role in treatment decisions and recovery prediction.

Main Methods:

  • Review of existing literature on cardiovascular magnetic resonance (CMR) in ischemic cardiomyopathy.
  • Analysis of CMR's capabilities in assessing cardiac function, perfusion, and tissue characteristics.
  • Examination of emerging quantitative and AI-based CMR methodologies.

Main Results:

  • CMR accurately assesses infarct characteristics (age, size) and complications in ischemic heart disease.
  • CMR provides precise data on cardiac function, perfusion, and tissue characterization.
  • Established roles in diagnosis, prognosis, treatment support, and recovery prediction are confirmed.

Conclusions:

  • Cardiovascular magnetic resonance (CMR) is indispensable for evaluating ischemic cardiomyopathy.
  • Emerging quantitative and AI approaches are set to enhance CMR's clinical impact.
  • CMR supports critical clinical decisions and predicts patient outcomes in heart failure.

Keywords:
cardiovascular magnetic resonanceischemic cardiomyopathyischemic heart disease

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