Comparison of SCORE, SCORE2 and Framingham Risk Score-Based Methods for Vascular Age Calculation

Helga Gyöngyösi1, Beáta Kőrösi1, Dóra Batta1

  • 1Department of Family Medicine, Semmelweis University, 1085 Budapest, Hungary.

PubMed

Insights

Different methods for calculating vascular age, including SCORE2 and Framingham Risk Score (FRS), often yield higher results than chronological age, especially in hypertensive individuals. Further research is needed to compare these vascular age calculation methods.

Area of Science:

  • Cardiology
  • Preventive Medicine
  • Health Risk Assessment

Background:

  • Vascular age calculation aids patient understanding of lifestyle and medication adherence.
  • Multiple methods exist for vascular age calculation, potentially yielding differing results.

Purpose of the Study:

  • To evaluate and compare vascular age estimations using the Systematic Coronary Risk Evaluation (SCORE), SCORE 2, and Framingham Risk Score (FRS) methods.

Main Methods:

  • Inclusion of subjects aged 40-65.
  • Calculation of vascular ages based on SCORE, SCORE2, and FRS methodologies.
  • Analysis of data from 141 participants, including those with hypertension and white-coat hypertension.

Main Results:

  • SCORE2 and FRS-derived vascular ages were consistently higher than chronological age in the general cohort.
  • Both SCORE2 and FRS indicated higher vascular ages than SCORE; FRS also exceeded SCORE2.
  • These discrepancies were observed in hypertensive and white-coat hypertensive groups, but not in healthy individuals.

Conclusions:

  • Significant differences exist between various vascular age calculation methods.
  • A notable proportion of subjects exhibited elevated vascular age.
  • Further comparative studies of different vascular age assessment tools are warranted.