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Comparison of SCORE, SCORE2 and Framingham Risk Score-Based Methods for Vascular Age Calculation
Helga Gyöngyösi1, Beáta Kőrösi1, Dóra Batta1
1Department of Family Medicine, Semmelweis University, 1085 Budapest, Hungary.
Insights
Different methods for calculating vascular age, including SCORE2 and Framingham Risk Score (FRS), often yield higher results than chronological age, especially in hypertensive individuals. Further research is needed to compare these vascular age calculation methods.
Area of Science:
- Cardiology
- Preventive Medicine
- Health Risk Assessment
Background:
- Vascular age calculation aids patient understanding of lifestyle and medication adherence.
- Multiple methods exist for vascular age calculation, potentially yielding differing results.
Purpose of the Study:
- To evaluate and compare vascular age estimations using the Systematic Coronary Risk Evaluation (SCORE), SCORE 2, and Framingham Risk Score (FRS) methods.
Main Methods:
- Inclusion of subjects aged 40-65.
- Calculation of vascular ages based on SCORE, SCORE2, and FRS methodologies.
- Analysis of data from 141 participants, including those with hypertension and white-coat hypertension.
Main Results:
- SCORE2 and FRS-derived vascular ages were consistently higher than chronological age in the general cohort.
- Both SCORE2 and FRS indicated higher vascular ages than SCORE; FRS also exceeded SCORE2.
- These discrepancies were observed in hypertensive and white-coat hypertensive groups, but not in healthy individuals.
Conclusions:
- Significant differences exist between various vascular age calculation methods.
- A notable proportion of subjects exhibited elevated vascular age.
- Further comparative studies of different vascular age assessment tools are warranted.
Abstract:
Background/objectives: Calculation of vascular age can help patients to understand the importance of adherence to a healthy lifestyle and medications. There are different methods of calculating vascular age, but different methods can provide different vascular age results. Our aim was to evaluate vascular age based on the Systematic Coronary Risk Evaluation (SCORE), Systematic Coronary Risk Evaluation 2 (SCORE 2) and Framingham Risk Score (FRS) methods. Methods: Subjects between the ages of 40-65 were involved. Vascular ages were defined based on SCORE, SCORE2 and FRS methods according to data from the literature. Results: In total, 141 patients were involved in the study; among them 94 had hypertension (HT) and 23 had white-coat hypertension. In the total population, SCORE2 and FRS vascular ages were higher compared to chronological age. SCORE2 and FRS vascular ages were higher than SCORE vascular age, and FRS vascular age was higher compared to SCORE2 as well. These tendencies were the same in the case of hypertensive patients and in patients with white-coat hypertension. In healthy patients, there were no differences between chronological age and vascular age. Conclusions: The differences found between the calculated vascular ages and the proportion of subjects with elevated vascular age warrant further comparison of different vascular age calculation methods.
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