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How the Latest Guidelines Are Changing the Diagnostic and Therapeutic Landscape of Arterial Hypertension
Maria Concetta Pastore1, Clarissa Carmona De Azevedo Bellagamba1, Riccardo Liga2
1Department of Medical Biotechnologies, Division of Cardiology, University of Siena, 53100 Siena, Italy.
Insights
New hypertension guidelines offer novel strategies but raise concerns about practical implementation. Experts discuss the pros and cons of these updated recommendations for managing arterial hypertension.
Area of Science:
- Cardiology
- Public Health
Background:
- Arterial hypertension (HTN) is a primary cardiovascular risk factor and a significant global health concern.
- Recent years have seen the release of updated international guidelines for HTN treatment from major cardiovascular societies.
Purpose of the Study:
- To analyze and discuss the novelties presented in the latest international hypertension guidelines.
- To evaluate the potential advantages and disadvantages of these new recommendations for clinical practice.
Main Methods:
- Review and critical analysis of recent guidelines from the European Society of Cardiology, European Society of Hypertension, and American College of Cardiology/American Heart Association.
- Discussion of key changes including screening emphasis, lower treatment targets, and resistant hypertension strategies.
Main Results:
- The new guidelines introduce significant changes, including intensified screening and lower blood pressure targets.
- Strategies for managing resistant hypertension are updated, prompting expert debate.
- Concerns exist regarding the clinical feasibility and practical application of these stringent recommendations.
Conclusions:
- The updated hypertension guidelines present both opportunities and challenges for patient management.
- Further discussion and evidence are needed to ensure the effective and feasible implementation of these recommendations in diverse clinical settings.
- Balancing guideline recommendations with real-world practice is crucial for addressing the global burden of arterial hypertension.
Abstract:
Arterial hypertension (HTN) represents the major cardiovascular risk factor and still represents a global health issue. In the last two years, three international societies published the new guidelines for the treatment of HTN (European Society of Cardiology, 2025; European Society of Hypertension, 2023; and American College of Cardiology in collaboration with American Heart Association, 2025), with many novelties which have been the object of many discussions among experts. The increased stress on screening programs, the new lower targets to reach by medical treatment, and the new strategies for resistant hypertension have raised some doubt on the feasibility of these recommendations in clinical practice. In this perspective document, the authors highlight and discuss the novelties and potential pros and cons of the new international recommendations for the treatment of arterial HTN.
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