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Next-Generation Spectacle Lenses for Myopia Control: Optical Designs, Mechanisms, and Clinical Efficacy.

Neeraj K Singh1, Pablo De Gracia2

  • 1Kentucky College of Optometry, University of Pikeville, Pikeville, KY 41501, USA.

Journal of Clinical Medicine
|November 13, 2025
PubMed
Summary

Next-generation spectacle lenses effectively slow myopia progression by 40-60% using advanced optical designs. These myopia control lenses offer a safe, comfortable, and compliant solution for managing rising global myopia rates.

Keywords:
myopiamyopic defocusoptical interventionsspectacle lenses

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Area of Science:

  • Ophthalmology
  • Optometry
  • Vision Science

Background:

  • Global myopia prevalence is increasing dramatically.
  • Effective interventions are crucial for myopia management.
  • Spectacle lens technology offers promising myopia control solutions.

Purpose of the Study:

  • To review next-generation spectacle lenses for myopia management.
  • To examine their optical principles, mechanisms, effectiveness, and safety.
  • To assess visual performance, compliance, and cosmetic aspects.

Main Methods:

  • Review of spectacle lenses with Defocus Incorporated Multiple Segments (DIMS), Highly Aspherical Lenslet Target (HALT), Diffusion Optics Technology (DOT), and Cylindrical Annular Refractive Element (CARE).
  • Analysis of clinical effectiveness, refractive progression, axial elongation, visual performance, and safety data.
  • Evaluation of wearer compliance and adaptation.

Main Results:

  • These lenses reduce refractive progression and axial elongation by 40-60% compared to single-vision lenses.
  • Optical strategies include simultaneous myopic defocus and peripheral contrast modulation.
  • High wearer compliance is noted due to visual comfort and aesthetics.

Conclusions:

  • Next-generation spectacle lenses are a promising, evidence-based myopia management strategy.
  • They offer sustained efficacy and safety with good visual performance.
  • Further research will refine their role in global myopia control.