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Updated: Jan 11, 2026

Induction and Assessment of Exertional Skeletal Muscle Damage in Humans
Published on: December 11, 2016
Effects of Acute Fish Oil Supplementation on Muscle Function and Soreness After Eccentric Contraction-Induced Muscle
Sang-Rok Lee1, Dean Directo2, Yangmi Kang3
1Department of Kinesiology, Samford University, Birmingham, AL 35229, USA.
Acute fish oil (FO) supplementation may modestly improve muscle recovery and reduce soreness after exercise-induced muscle damage (EIMD) in young adults. However, the overall impact of FO on EIMD appears limited.
Area of Science:
- Exercise Physiology
- Nutritional Science
- Sports Medicine
Background:
- Exercise-induced muscle damage (EIMD) is a common response to strenuous physical activity.
- Fish oil (FO) supplementation is explored for its anti-inflammatory and muscle-protective properties.
- Understanding the efficacy of acute FO supplementation on EIMD recovery is crucial for athletes and active individuals.
Purpose of the Study:
- To determine the efficacy of acute fish oil (FO) supplementation on indices of exercise-induced muscle damage (EIMD).
- To assess the impact of FO on muscle function recovery, soreness, and systemic inflammation markers in young healthy adults.
Main Methods:
- Twenty-two healthy young adults were randomized into fish oil (FO) or placebo (CON) groups.
- Participants completed a plyometric drop jump protocol to induce EIMD.
- Muscle function (vertical jump, MVC torque), soreness, and inflammation markers were measured pre- and post-exercise at various time points.
Main Results:
- The FO group showed faster recovery of vertical jump height and quadriceps peak torque compared to the CON group.
- Hamstring torque recovery was also enhanced in the FO group.
- Muscle soreness was significantly lower in the FO group at 48 hours post-exercise, and while TNF-α increased in both groups, the CON group showed a trend toward incomplete recovery.
Conclusions:
- Acute fish oil (FO) supplementation may offer modest benefits in aiding muscle recovery and reducing muscle soreness following EIMD.
- The overall impact of FO on EIMD indices in healthy young adults appears to be limited.
- Further research may be warranted to explore optimal dosages and specific populations for FO supplementation in EIMD recovery.
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