Long-standing macular cherry red spot - A case series and review of literature

Cherry red spot (CRS) is a characteristic ophthalmoscopic finding associated with conditions causing retinal ischemia or accumulation of different materials in the retinal nerve fiber layer. We report a retrospective series of three cases with late presentation of bilateral CRS and varied systemic associations. In these long-standing cases, the abnormal deposits remain localised to a small area around the fovea-either due to milder variant of the systemic disease or long-standing nature leading to decrease in deposits. Imaging tools such as fundus autofluorescence and optical coherence tomography help to support the diagnosis where genetic and histopathological examination is not possible.