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Nonpenetrating deep sclerectomy: Challenges, innovations, and current evidence
1Department of Ophthalmology, Cairo University, Giza, Egypt.
Oman Journal of Ophthalmology
|November 13, 2025
Summary
Nonpenetrating deep sclerectomy (NPDS) offers a safe and effective glaucoma treatment, gradually lowering intraocular pressure. This review explores NPDS techniques, innovations, and outcomes across various glaucoma types and stages.
Area of Science:
- Ophthalmology
- Glaucoma Surgery
Background:
- Nonpenetrating deep sclerectomy (NPDS) is a surgical technique developed in 1989.
- It is recognized for its favorable safety profile and efficacy in managing glaucoma.
- NPDS facilitates a controlled, gradual reduction in intraocular pressure compared to other procedures.
Purpose of the Study:
- To review the technique of Nonpenetrating deep sclerectomy (NPDS).
- To summarize challenges, innovations, and outcomes associated with NPDS.
- To cover NPDS applications in various glaucoma types and disease stages.
Main Methods:
- Literature review of Nonpenetrating deep sclerectomy (NPDS).
Main Results:
- NPDS demonstrates significant safety and good efficacy.
- The procedure leads to a controlled and gradual reduction of intraocular pressure.
- Evidence supports NPDS for various glaucomas and disease stages.
Conclusions:
- Nonpenetrating deep sclerectomy (NPDS) is a valuable surgical option for glaucoma.
- Ongoing innovations continue to refine NPDS techniques and outcomes.
- Further research can optimize NPDS for diverse patient populations and glaucoma severities.
Keywords:
Ahmed sutureglaucomaintraocular pressurenonpenetrating deep sclerectomyprimary open-angle glaucomasutureless nonpenetrating glaucoma surgery
